Cargando…

Mechanisms of Kappa Opioid Receptor Potentiation of Dopamine D2 Receptor Function in Quinpirole-Induced Locomotor Sensitization in Rats

BACKGROUND: Increased locomotor activity in response to the same stimulus is an index of behavioral sensitization observed in preclinical models of drug addiction and compulsive behaviors. Repeated administration of quinpirole, a D2/D3 dopamine agonist, induces locomotor sensitization. This effect i...

Descripción completa

Detalles Bibliográficos
Autores principales: Escobar, Angélica P, González, Marcela P, Meza, Rodrigo C, Noches, Verónica, Henny, Pablo, Gysling, Katia, España, Rodrigo A, Fuentealba, José A, Andrés,, María E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569963/
https://www.ncbi.nlm.nih.gov/pubmed/28531297
http://dx.doi.org/10.1093/ijnp/pyx042