Label-free, direct localization and relative quantitation of the RNA nucleobase methylations m(6)A, m(5)C, m(3)U, and m(5)U by top-down mass spectrometry

Nucleobase methylations are ubiquitous posttranscriptional modifications of ribonucleic acids (RNA) that can substantially increase the structural diversity of RNA in a highly dynamic fashion with implications for gene expression and human disease. However, high throughput, deep sequencing does not...

Descripción completa

Detalles Bibliográficos
Autores principales: Glasner, Heidelinde, Riml, Christian, Micura, Ronald, Breuker, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570050/
https://www.ncbi.nlm.nih.gov/pubmed/28549193
http://dx.doi.org/10.1093/nar/gkx470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570050/
https://www.ncbi.nlm.nih.gov/pubmed/28549193
http://dx.doi.org/10.1093/nar/gkx470

Ejemplares similares