Adaptive HIV-1 evolutionary trajectories are constrained by protein stability

Despite the use of combination antiretroviral drugs for the treatment of HIV-1 infection, the emergence of drug resistance remains a problem. Resistance may be conferred either by a single mutation or a concerted set of mutations. The involvement of multiple mutations can arise due to interactions b...

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Detalles Bibliográficos
Autores principales: Olabode, Abayomi S., Kandathil, Shaun M., Lovell, Simon C., Robertson, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570062/
https://www.ncbi.nlm.nih.gov/pubmed/28852572
http://dx.doi.org/10.1093/ve/vex019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570062/
https://www.ncbi.nlm.nih.gov/pubmed/28852572
http://dx.doi.org/10.1093/ve/vex019

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