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Position Matters: Network Centrality Considerably Impacts Rates of Protein Evolution in the Human Protein–Protein Interaction Network

The proteins of any organism evolve at disparate rates. A long list of factors affecting rates of protein evolution have been identified. However, the relative importance of each factor in determining rates of protein evolution remains unresolved. The prevailing view is that evolutionary rates are d...

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Detalles Bibliográficos
Autores principales: Alvarez-Ponce, David, Feyertag, Felix, Chakraborty, Sandip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570066/
https://www.ncbi.nlm.nih.gov/pubmed/28854629
http://dx.doi.org/10.1093/gbe/evx117