Intrinsically disordered RGG/RG domains mediate degenerate specificity in RNA binding

RGG/RG domains are the second most common RNA binding domain in the human genome, yet their RNA-binding properties remain poorly understood. Here, we report a detailed analysis of the RNA binding characteristics of intrinsically disordered RGG/RG domains from Fused in Sarcoma (FUS), FMRP and hnRNPU....

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Detalles Bibliográficos
Autores principales: Ozdilek, Bagdeser A., Thompson, Valery F., Ahmed, Nasiha S., White, Connor I., Batey, Robert T., Schwartz, Jacob C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570134/
https://www.ncbi.nlm.nih.gov/pubmed/28575444
http://dx.doi.org/10.1093/nar/gkx460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570134/
https://www.ncbi.nlm.nih.gov/pubmed/28575444
http://dx.doi.org/10.1093/nar/gkx460

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