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Intrinsically disordered RGG/RG domains mediate degenerate specificity in RNA binding
RGG/RG domains are the second most common RNA binding domain in the human genome, yet their RNA-binding properties remain poorly understood. Here, we report a detailed analysis of the RNA binding characteristics of intrinsically disordered RGG/RG domains from Fused in Sarcoma (FUS), FMRP and hnRNPU....
Autores principales: | Ozdilek, Bagdeser A., Thompson, Valery F., Ahmed, Nasiha S., White, Connor I., Batey, Robert T., Schwartz, Jacob C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570134/ https://www.ncbi.nlm.nih.gov/pubmed/28575444 http://dx.doi.org/10.1093/nar/gkx460 |
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