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GPCR-SSFE 2.0—a fragment-based molecular modeling web tool for Class A G-protein coupled receptors

G-protein coupled receptors (GPCRs) are key players in signal transduction and therefore a large proportion of pharmaceutical drugs target these receptors. Structural data of GPCRs are sparse yet important for elucidating the molecular basis of GPCR-related diseases and for performing structure-base...

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Detalles Bibliográficos
Autores principales: Worth, Catherine L., Kreuchwig, Franziska, Tiemann, Johanna K.S., Kreuchwig, Annika, Ritschel, Michele, Kleinau, Gunnar, Hildebrand, Peter W., Krause, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570183/
https://www.ncbi.nlm.nih.gov/pubmed/28582569
http://dx.doi.org/10.1093/nar/gkx399