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GPCR-SSFE 2.0—a fragment-based molecular modeling web tool for Class A G-protein coupled receptors
G-protein coupled receptors (GPCRs) are key players in signal transduction and therefore a large proportion of pharmaceutical drugs target these receptors. Structural data of GPCRs are sparse yet important for elucidating the molecular basis of GPCR-related diseases and for performing structure-base...
Autores principales: | Worth, Catherine L., Kreuchwig, Franziska, Tiemann, Johanna K.S., Kreuchwig, Annika, Ritschel, Michele, Kleinau, Gunnar, Hildebrand, Peter W., Krause, Gerd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570183/ https://www.ncbi.nlm.nih.gov/pubmed/28582569 http://dx.doi.org/10.1093/nar/gkx399 |
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