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Histologic and biochemical alterations predict pulmonary mechanical dysfunction in aging mice with chronic lung inflammation
Both aging and chronic inflammation produce complex structural and biochemical alterations to the lung known to impact work of breathing. Mice deficient in surfactant protein D (Sftpd) develop progressive age-related lung pathology characterized by tissue destruction/remodeling, accumulation of foam...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570219/ https://www.ncbi.nlm.nih.gov/pubmed/28837561 http://dx.doi.org/10.1371/journal.pcbi.1005570 |