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Histologic and biochemical alterations predict pulmonary mechanical dysfunction in aging mice with chronic lung inflammation

Both aging and chronic inflammation produce complex structural and biochemical alterations to the lung known to impact work of breathing. Mice deficient in surfactant protein D (Sftpd) develop progressive age-related lung pathology characterized by tissue destruction/remodeling, accumulation of foam...

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Detalles Bibliográficos
Autores principales:	Massa, Christopher B., Groves, Angela M., Jaggernauth, Smita U., Laskin, Debra L., Gow, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570219/ https://www.ncbi.nlm.nih.gov/pubmed/28837561 http://dx.doi.org/10.1371/journal.pcbi.1005570

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