Alternative vaccine administration by powder injection: Needle-free dermal delivery of the glycoconjugate meningococcal group Y vaccine

Powder-injectors use gas propulsion to deposit lyophilised drug or vaccine particles in the epidermal and sub epidermal layers of the skin. We prepared dry-powder (T(g) = 45.2 ± 0.5°C) microparticles (58.1 μm) of a MenY-CRM(197) glyconjugate vaccine (0.5% wt.) for intradermal needle-free powder inje...

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Detalles Bibliográficos
Autores principales: Weissmueller, Nikolas T., Marsay, Leanne, Schiffter, Heiko A., Carlisle, Robert C., Rollier, Christine S., Prud’homme, Robert K., Pollard, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570268/
https://www.ncbi.nlm.nih.gov/pubmed/28837693
http://dx.doi.org/10.1371/journal.pone.0183427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570268/
https://www.ncbi.nlm.nih.gov/pubmed/28837693
http://dx.doi.org/10.1371/journal.pone.0183427

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