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Alternative vaccine administration by powder injection: Needle-free dermal delivery of the glycoconjugate meningococcal group Y vaccine
Powder-injectors use gas propulsion to deposit lyophilised drug or vaccine particles in the epidermal and sub epidermal layers of the skin. We prepared dry-powder (T(g) = 45.2 ± 0.5°C) microparticles (58.1 μm) of a MenY-CRM(197) glyconjugate vaccine (0.5% wt.) for intradermal needle-free powder inje...
Autores principales: | Weissmueller, Nikolas T., Marsay, Leanne, Schiffter, Heiko A., Carlisle, Robert C., Rollier, Christine S., Prud’homme, Robert K., Pollard, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570268/ https://www.ncbi.nlm.nih.gov/pubmed/28837693 http://dx.doi.org/10.1371/journal.pone.0183427 |
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