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Lef1-dependent hypothalamic neurogenesis inhibits anxiety

While innate behaviors are conserved throughout the animal kingdom, it is unknown whether common signaling pathways regulate the development of neuronal populations mediating these behaviors in diverse organisms. Here, we demonstrate that the Wnt/ß-catenin effector Lef1 is required for the different...

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Detalles Bibliográficos
Autores principales: Xie, Yuanyuan, Kaufmann, Dan, Moulton, Matthew J., Panahi, Samin, Gaynes, John A., Watters, Harrison N., Zhou, Dingxi, Xue, Hai-Hui, Fung, Camille M., Levine, Edward M., Letsou, Anthea, Brennan, K. C., Dorsky, Richard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570277/
https://www.ncbi.nlm.nih.gov/pubmed/28837622
http://dx.doi.org/10.1371/journal.pbio.2002257