Cargando…

LL-37 causes cell death of human nasal epithelial cells, which is inhibited with a synthetic glycosaminoglycan

LL-37 is an immune peptide that regulates innate and adaptive immune responses in the upper airways. Elevated levels of LL-37 have been linked to cell death and inflammatory diseases, such as chronic rhinosinusitis (CRS). Glycosaminoglycans (GAGs) are polysaccharides that are found on respiratory ep...

Descripción completa

Detalles Bibliográficos
Autores principales: Thomas, Andrew J., Pulsipher, Abigail, Davis, Brock M., Alt, Jeremiah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570287/
https://www.ncbi.nlm.nih.gov/pubmed/28837619
http://dx.doi.org/10.1371/journal.pone.0183542