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ALK signaling cascade confers multiple advantages to glioblastoma cells through neovascularization and cell proliferation
Anaplastic lymphoma kinase (ALK), which is a receptor tyrosine kinase, is essentially and transiently expressed in the developing nervous system. Here we examined the functional role of the ALK gene in glioblastomas (GBMs). In clinical samples of GBMs, high ALK expression without gene rearrangements...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570309/ https://www.ncbi.nlm.nih.gov/pubmed/28837676 http://dx.doi.org/10.1371/journal.pone.0183516 |