Exploring virus release as a bottleneck for the spread of influenza A virus infection in vitro and the implications for antiviral therapy with neuraminidase inhibitors

Mathematical models (MMs) have been used to study the kinetics of influenza A virus infections under antiviral therapy, and to characterize the efficacy of antivirals such as neuraminidase inhibitors (NAIs). NAIs prevent viral neuraminidase from cleaving sialic acid receptors that bind virus progeny...

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Detalles Bibliográficos
Autores principales: Liao, Laura E., Kowal, Szymon, Cardenas, Daniel A., Beauchemin, Catherine A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570347/
https://www.ncbi.nlm.nih.gov/pubmed/28837615
http://dx.doi.org/10.1371/journal.pone.0183621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570347/
https://www.ncbi.nlm.nih.gov/pubmed/28837615
http://dx.doi.org/10.1371/journal.pone.0183621

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