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Cardiac transcriptome profiling of diabetic Akita mice using microarray and next generation sequencing
Although diabetes mellitus (DM) causes cardiomyopathy and exacerbates heart failure, the underlying molecular mechanisms for diabetic cardiomyopathy/heart failure are poorly understood. Insulin2 mutant (Ins2(+/-)) Akita is a mouse model of T1DM, which manifests cardiac dysfunction. However, molecula...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570368/ https://www.ncbi.nlm.nih.gov/pubmed/28837672 http://dx.doi.org/10.1371/journal.pone.0182828 |