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Cardiac transcriptome profiling of diabetic Akita mice using microarray and next generation sequencing

Although diabetes mellitus (DM) causes cardiomyopathy and exacerbates heart failure, the underlying molecular mechanisms for diabetic cardiomyopathy/heart failure are poorly understood. Insulin2 mutant (Ins2(+/-)) Akita is a mouse model of T1DM, which manifests cardiac dysfunction. However, molecula...

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Detalles Bibliográficos
Autores principales:	Kesherwani, Varun, Shahshahan, Hamid R., Mishra, Paras K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570368/ https://www.ncbi.nlm.nih.gov/pubmed/28837672 http://dx.doi.org/10.1371/journal.pone.0182828

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