A validated LC-MS/MS method for cellular thyroid hormone metabolism: Uptake and turnover of mono-iodinated thyroid hormone metabolites by PCCL3 thyrocytes

Tyrosine and phenolic ring de-iodination of thyroid hormones (TH) is crucial for regulating their physiological activity. Furthermore, reactions such as de-carboxylation to thyronamines (TAM) and de-amination to thyroacetic acids (TAc) produce TH metabolites (THM) with distinct biological properties...

Descripción completa

Detalles Bibliográficos
Autores principales: Richards, Keith H., Schanze, Nancy, Monk, Ray, Rijntjes, Eddy, Rathmann, Daniel, Köhrle, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570372/
https://www.ncbi.nlm.nih.gov/pubmed/28837607
http://dx.doi.org/10.1371/journal.pone.0183482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570372/
https://www.ncbi.nlm.nih.gov/pubmed/28837607
http://dx.doi.org/10.1371/journal.pone.0183482

Ejemplares similares