GSTM1/GSTT1 double-null genotype increases risk of treatment-resistant schizophrenia: A genetic association study in Brazilian patients

BACKGROUND: The role of oxidative stress in schizophrenia has been demonstrated, particularly in subjects with treatment-resistant schizophrenia (TRS). In such patients, the decreased levels of antioxidants in conjunction with the increased generation of reactive oxygen species in the brain exposes...

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Detalles Bibliográficos
Autores principales: Pinheiro, Denise S., Santos, Rodrigo da S., de Brito, Rodrigo B., Cruz, Aline Helena da S., Ghedini, Paulo C., Reis, Angela A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570380/
https://www.ncbi.nlm.nih.gov/pubmed/28837637
http://dx.doi.org/10.1371/journal.pone.0183812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570380/
https://www.ncbi.nlm.nih.gov/pubmed/28837637
http://dx.doi.org/10.1371/journal.pone.0183812

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