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A systems approach reveals distinct metabolic strategies among the NCI-60 cancer cell lines

The metabolic phenotype of cancer cells is reflected by the metabolites they consume and by the byproducts they release. Here, we use quantitative, extracellular metabolomic data of the NCI-60 panel and a novel computational method to generate 120 condition-specific cancer cell line metabolic models...

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Detalles Bibliográficos
Autores principales: Aurich, Maike K., Fleming, Ronan M. T., Thiele, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570491/
https://www.ncbi.nlm.nih.gov/pubmed/28806730
http://dx.doi.org/10.1371/journal.pcbi.1005698