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A systems approach reveals distinct metabolic strategies among the NCI-60 cancer cell lines
The metabolic phenotype of cancer cells is reflected by the metabolites they consume and by the byproducts they release. Here, we use quantitative, extracellular metabolomic data of the NCI-60 panel and a novel computational method to generate 120 condition-specific cancer cell line metabolic models...
Autores principales: | Aurich, Maike K., Fleming, Ronan M. T., Thiele, Ines |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570491/ https://www.ncbi.nlm.nih.gov/pubmed/28806730 http://dx.doi.org/10.1371/journal.pcbi.1005698 |
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