Cargando…

Persistent mycobacteria evade an antibacterial program mediated by phagolysosomal TLR7/8/MyD88 in human primary macrophages

Pathogenic mycobacteria reside in macrophages where they avoid lysosomal targeting and degradation through poorly understood mechanisms proposed to involve arrest of phagosomal maturation at an early endosomal stage. A clear understanding of how this relates to host defenses elicited from various in...

Descripción completa

Detalles Bibliográficos
Autores principales: Gidon, Alexandre, Åsberg, Signe Elisabeth, Louet, Claire, Ryan, Liv, Haug, Markus, Flo, Trude Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570494/
https://www.ncbi.nlm.nih.gov/pubmed/28806745
http://dx.doi.org/10.1371/journal.ppat.1006551