NFATc2 enhances tumor-initiating phenotypes through the NFATc2/SOX2/ALDH axis in lung adenocarcinoma

Tumor-initiating cells (TIC) are dynamic cancer cell subsets that display enhanced tumor functions and resilience to treatment but the mechanism of TIC induction or maintenance in lung cancer is not fully understood. In this study, we show the calcium pathway transcription factor NFATc2 is a novel r...

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Detalles Bibliográficos
Autores principales: Xiao, Zhi-Jie, Liu, Jing, Wang, Si-Qi, Zhu, Yun, Gao, Xu-Yuan, Tin, Vicky Pui-Chi, Qin, Jing, Wang, Jun-Wen, Wong, Maria Pik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570574/
https://www.ncbi.nlm.nih.gov/pubmed/28737489
http://dx.doi.org/10.7554/eLife.26733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570574/
https://www.ncbi.nlm.nih.gov/pubmed/28737489
http://dx.doi.org/10.7554/eLife.26733

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