Effect of HPV E6/E7 siRNA with Chemotherapeutic Agents on the Regulation of TP53/E2F Dynamic Behavior for Cell Fate Decisions

Toxicity and resistance remain major challenges for advanced or recurrent cervical cancer therapies, as treatment requires high doses of chemotherapeutic agents. Restoration of TP53 and hypophosphorylated-retinoblastoma (pRB) proteins by human papillomavirus (HPV) E6/E7 siRNA sensitizes HPV-positive...

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Detalles Bibliográficos
Autores principales: Rajasekaran, Nirmal, Jung, Hun Soon, Bae, Soo Hyeon, Chelakkot, Chaithanya, Hong, Sungyoul, Choi, Jong-Sun, Yim, Dong-Seok, Oh, Yu-Kyoung, Choi, Yoon-La, Shin, Young Kee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570578/
https://www.ncbi.nlm.nih.gov/pubmed/28843398
http://dx.doi.org/10.1016/j.neo.2017.07.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570578/
https://www.ncbi.nlm.nih.gov/pubmed/28843398
http://dx.doi.org/10.1016/j.neo.2017.07.005

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