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Assessment of Response of Kidney Tumors to Rapamycin and Atorvastatin in Tsc1(+/−) Mice

Atorvastatin is widely used to lower blood cholesterol and to reduce risk of cardiovascular disease–associated complications. Epidemiological investigations and preclinical studies suggest that statins such as atorvastatin have antitumor activity for various types of cancer. Tuberous sclerosis (TSC)...

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Detalles Bibliográficos
Autores principales: Shen, Ming Hong, Samsel, Paulina, Shen, Louise L., Narov, Kalin, Yang, Jian, Sampson, Julian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570581/
https://www.ncbi.nlm.nih.gov/pubmed/28844017
http://dx.doi.org/10.1016/j.tranon.2017.07.009