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Aberrant control of NF-κB in cancer permits transcriptional and phenotypic plasticity, to curtail dependence on host tissue: molecular mode
The role of the transcription factor NF-κB in shaping the cancer microenvironment is becoming increasingly clear. Inflammation alters the activity of enzymes that modulate NF-κB function, and causes extensive changes in genomic chromatin that ultimately drastically alter cell-specific gene expressio...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Chinese Anti-Cancer Association
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570602/ https://www.ncbi.nlm.nih.gov/pubmed/28884042 http://dx.doi.org/10.20892/j.issn.2095-3941.2017.0029 |