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Tumor-derived fibulin-3 activates pro-invasive NF-kappa B signaling in glioblastoma cells and their microenvironment

Molecular profiling of glioblastomas has revealed the presence of key signaling hubs that contribute to tumor progression and acquisition of resistance. One of these main signaling mechanisms is the NF-κB pathway, which integrates multiple extracellular signals into transcriptional programs for tumo...

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Detalles Bibliográficos
Autores principales: Nandhu, Mohan Sobhana, Kwiatkowska, Aneta, Bhaskaran, Vivek, Hayes, Josie, Hu, Bin, Viapiano, Mariano S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570669/
https://www.ncbi.nlm.nih.gov/pubmed/28414309
http://dx.doi.org/10.1038/onc.2017.109