Cargando…

Tumor-derived fibulin-3 activates pro-invasive NF-kappa B signaling in glioblastoma cells and their microenvironment

Molecular profiling of glioblastomas has revealed the presence of key signaling hubs that contribute to tumor progression and acquisition of resistance. One of these main signaling mechanisms is the NF-κB pathway, which integrates multiple extracellular signals into transcriptional programs for tumo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nandhu, Mohan Sobhana, Kwiatkowska, Aneta, Bhaskaran, Vivek, Hayes, Josie, Hu, Bin, Viapiano, Mariano S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570669/ https://www.ncbi.nlm.nih.gov/pubmed/28414309 http://dx.doi.org/10.1038/onc.2017.109

Ejemplares similares

Strategies in Gene Therapy for Glioblastoma
por: Kwiatkowska, Aneta, et al.
Publicado: (2013)

The extracellular matrix protein fibulin-3/EFEMP1 promotes pleural mesothelioma growth by activation of PI3K/Akt signaling
por: Roshini, Arivazhagan, et al.
Publicado: (2022)

Novel Associations Within the Tumor Microenvironment: Fibulins Meet ADAMTSs
por: Fontanil, Tania, et al.
Publicado: (2019)

Fibulin-3 is a Novel TGF-β pathway Inhibitor in the Breast Cancer Microenvironment
por: Tian, Hongyu, et al.
Publicado: (2015)

Fibulin-5 for youthful skin
por: Williams, Ruth
Publicado: (2007)

The Pathophysiological Significance of Fibulin-3
por: Livingstone, Imogen, et al.
Publicado: (2020)

Roles of Fibulin-2 in Carcinogenesis
por: Zhang, Huayue, et al.
Publicado: (2020)

Fibulin-4 and -5, but not Fibulin-2, are Associated with Tropoelastin Deposition in Elastin-Producing Cell Culture
por: Yamauchi, Yoshinori, et al.
Publicado: (2010)

NF-kappaB in Lung Tumorigenesis
por: Cai, Zhenjian, et al.
Publicado: (2011)

Correlation of Fibulin-2 expression with proliferation, migration and invasion of breast cancer cells
por: Zhang, Xiliang, et al.
Publicado: (2020)

Fibulin-2 expression associates with vascular invasion and patient survival in breast cancer
por: Klingen, Tor A., et al.
Publicado: (2021)

Fibulin-6 regulates pro-fibrotic TGF-β responses in neonatal mouse ventricular cardiac fibroblasts
por: Chowdhury, Arpita, et al.
Publicado: (2017)

An Investigation of Fibulin-2 in Hypertrophic Cardiomyopathy
por: Ibrahim, Ayman M., et al.
Publicado: (2020)

Haloperidol Suppresses NF-kappaB to Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Response in RAW 264 Cells
por: Yamamoto, Shunsuke, et al.
Publicado: (2016)

Dual antivascular function of human fibulin‐3 variant, a potential new drug discovery strategy for glioblastoma
por: Ke, Chao, et al.
Publicado: (2020)

The small GTPase RhoG mediates glioblastoma cell invasion
por: Kwiatkowska, Aneta, et al.
Publicado: (2012)

Pro-inflammatory gene expression in solid glioblastoma microenvironment and in hypoxic stem cells from human glioblastoma
por: Tafani, Marco, et al.
Publicado: (2011)

NF-kappa B and I kappa B alpha: an inducible regulatory system in endothelial activation
Publicado: (1994)

Wedelolactone inhibits LPS-induced pro-inflammation via NF-kappaB Pathway in RAW 264.7 cells
por: Yuan, Fang, et al.
Publicado: (2013)

Glioblastoma Microenvironment and Invasiveness: New Insights and Therapeutic Targets
por: Erices, José Ignacio, et al.
Publicado: (2023)

NF-kappaB and cytokines in pancreatic acinar cells.
por: Kim, H, et al.
Publicado: (2000)

Asterias rubens: Evidence of NF-kappa B genes
por: Leclerc, Michel, et al.
Publicado: (2016)

NF-kappaB: Two Sides of the Same Coin
por: Pires, Bruno R. B., et al.
Publicado: (2018)

An Update on the Multifaceted Role of NF-kappaB in Endometriosis
por: Liu, Yuanmeng, et al.
Publicado: (2022)

Nuclear factor kappaB (NF-kappaB) pathway as a therapeutic target in rheumatoid arthritis.
por: Jue, D. M., et al.
Publicado: (1999)

KSHV regulation of fibulins in Kaposi’s sarcoma: implications for tumorigenesis
por: Alcendor, Donald, et al.
Publicado: (2010)

Comparison of fibulin-3 and mesothelin as markers in malignant mesothelioma
por: Creaney, Jenette, et al.
Publicado: (2014)

The role of adhesion protein Fibulin7 in development and diseases
por: Chakraborty, Papiya, et al.
Publicado: (2020)

Fibulin-2 Facilitates Malignant Progression of Hepatocellular Carcinoma
por: Hu, Xinyan, et al.
Publicado: (2023)

Fibulin1 and mesothelin expressions in pancreas ductal adenocarcinoma
por: Aksoy, Asude, et al.
Publicado: (2023)

Hyaluronan fragments activate an NF-kappa B/I-kappa B alpha autoregulatory loop in murine macrophages
Publicado: (1996)

T cell-dependent induction of NF-kappa B in B cells
Publicado: (1993)

Recent insights into the role of NF-kappaB in ovarian carcinogenesis
por: Alvero, Ayesha B
Publicado: (2010)

Interactions among oscillatory pathways in NF-kappa B signaling
por: Wang, Yunjiao, et al.
Publicado: (2011)

NF-kappaB Signaling in Chronic Inflammatory Airway Disease
por: Schuliga, Michael
Publicado: (2015)

Inhibition of NF-kappa B pathway leads to deregulation of epithelial-mesenchymal transition and neural invasion in pancreatic cancer
por: Nomura, Alice, et al.
Publicado: (2016)

TNF-Alpha Promotes Invasion and Metastasis via NF-Kappa B Pathway in Oral Squamous Cell Carcinoma
por: Tang, Daofang, et al.
Publicado: (2017)

PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival
por: Ding, Zonghui, et al.
Publicado: (2018)

Inhibition of I kappa B-alpha phosphorylation and degradation and subsequent NF-kappa B activation by glutathione peroxidase overexpression
Publicado: (1996)

Fibulin-5 inhibits hepatocellular carcinoma cell migration and invasion by down-regulating matrix metalloproteinase-7 expression
por: Tu, Kangsheng, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_5esou05pnslrg8qs39gnlofrq6