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Indole-based perenosins as highly potent HCl transporters and potential anti-cancer agents
Prodigiosin is one of the most potent anion transporters in lipid bilayer membranes reported to date. Inspired by the structure of this natural product, we have recently designed and synthesised a new class of H(+)/Cl(−) cotransporters named ‘perenosins’. Here we report a new library of indole-based...
Autores principales: | Jowett, Laura A., Howe, Ethan N. W., Soto-Cerrato, Vanessa, Van Rossom, Wim, Pérez-Tomás, Ricardo, Gale, Philip A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570892/ https://www.ncbi.nlm.nih.gov/pubmed/28839192 http://dx.doi.org/10.1038/s41598-017-09645-9 |
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