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BIRC3 is a biomarker of mesenchymal habitat of glioblastoma, and a mediator of survival adaptation in hypoxia-driven glioblastoma habitats

Tumor hypoxia is an established facilitator of survival adaptation and mesenchymal transformation in glioblastoma (GBM). The underlying mechanisms that direct hypoxia-mediated survival in GBM habitats are unclear. We previously identified BIRC3 as a mediator of therapeutic resistance in GBM to stand...

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Detalles Bibliográficos
Autores principales: Wang, Dapeng, Berglund, Anders E., Kenchappa, Rajappa S., MacAulay, Robert J., Mulé, James J., Etame, Arnold B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570925/
https://www.ncbi.nlm.nih.gov/pubmed/28839258
http://dx.doi.org/10.1038/s41598-017-09503-8