Activation of autophagy attenuates EtOH-LPS-induced hepatic steatosis and injury through MD2 associated TLR4 signaling

Autophagy serves as a protective mechanism to degrade damaged organelles and proteins. Acute alcohol exposure is known to activate the hepatic autophagy response, whereas chronic alcohol exposure slows autophagosome formation along with an elevation of gut-derived endotoxin. In the current study, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Kong, Xiaoxia, Yang, Ying, Ren, Li, Shao, Tuo, Li, Fengyuan, Zhao, Cuiqing, Liu, Liming, Zhang, Hongyu, McClain, Craig J., Feng, Wenke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571015/
https://www.ncbi.nlm.nih.gov/pubmed/28839246
http://dx.doi.org/10.1038/s41598-017-09045-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571015/
https://www.ncbi.nlm.nih.gov/pubmed/28839246
http://dx.doi.org/10.1038/s41598-017-09045-z

Ejemplares similares