Cargando…
The role of the immunoproteasome in interferon-γ-mediated microglial activation
Microglia regulate the brain microenvironment by sensing damage and neutralizing potentially harmful insults. Disruption of central nervous system (CNS) homeostasis results in transition of microglia to a reactive state characterized by morphological changes and production of cytokines to prevent fu...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571106/ https://www.ncbi.nlm.nih.gov/pubmed/28839214 http://dx.doi.org/10.1038/s41598-017-09715-y |