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The role of the immunoproteasome in interferon-γ-mediated microglial activation
Microglia regulate the brain microenvironment by sensing damage and neutralizing potentially harmful insults. Disruption of central nervous system (CNS) homeostasis results in transition of microglia to a reactive state characterized by morphological changes and production of cytokines to prevent fu...
Autores principales: | Moritz, Kasey E., McCormack, Nikki M., Abera, Mahlet B., Viollet, Coralie, Yauger, Young J., Sukumar, Gauthaman, Dalgard, Clifton L., Burnett, Barrington G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571106/ https://www.ncbi.nlm.nih.gov/pubmed/28839214 http://dx.doi.org/10.1038/s41598-017-09715-y |
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