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MicroRNA-204 promotes vascular endoplasmic reticulum stress and endothelial dysfunction by targeting Sirtuin1

Endoplasmic reticulum (ER) stress has been implicated in vascular endothelial dysfunction of obesity, diabetes, and hypertension. MicroRNAs play an important role in regulating ER stress. Here we show that microRNA-204 (miR-204) promotes vascular ER stress and endothelial dysfunction by targeting th...

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Detalles Bibliográficos
Autores principales: Kassan, Modar, Vikram, Ajit, Li, Qiuxia, Kim, Young-Rae, Kumar, Santosh, Gabani, Mohanad, Liu, Jing, Jacobs, Julia S., Irani, Kaikobad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571183/
https://www.ncbi.nlm.nih.gov/pubmed/28839162
http://dx.doi.org/10.1038/s41598-017-06721-y