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Urokinase-type plasminogen activator receptor (uPAR) expression enhances invasion and metastasis in RAS mutated tumors

The urokinase-type plasminogen activator receptor (uPAR) is a GPI-anchored cell membrane receptor that focuses urokinase (uPA) proteolytic activity on the cell surface. Its expression is increased in many human cancers, including non-small cell lung cancer (NSCLC) and colorectal cancer (CRC), and co...

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Detalles Bibliográficos
Autores principales: Mauro, Concetta Di, Pesapane, Ada, Formisano, Luigi, Rosa, Roberta, D’Amato, Valentina, Ciciola, Paola, Servetto, Alberto, Marciano, Roberta, Orsini, Roberta Clara, Monteleone, Francesca, Zambrano, Nicola, Fontanini, Gabriella, Servadio, Adele, Pignataro, Giuseppe, Grumetto, Lucia, Lavecchia, Antonio, Bruzzese, Dario, Iaccarino, Antonino, Troncone, Giancarlo, Veneziani, Bianca Maria, Montuori, Nunzia, Placido, Sabino De, Bianco, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571185/
https://www.ncbi.nlm.nih.gov/pubmed/28839232
http://dx.doi.org/10.1038/s41598-017-10062-1