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Urokinase-type plasminogen activator receptor (uPAR) expression enhances invasion and metastasis in RAS mutated tumors
The urokinase-type plasminogen activator receptor (uPAR) is a GPI-anchored cell membrane receptor that focuses urokinase (uPA) proteolytic activity on the cell surface. Its expression is increased in many human cancers, including non-small cell lung cancer (NSCLC) and colorectal cancer (CRC), and co...
Autores principales: | Mauro, Concetta Di, Pesapane, Ada, Formisano, Luigi, Rosa, Roberta, D’Amato, Valentina, Ciciola, Paola, Servetto, Alberto, Marciano, Roberta, Orsini, Roberta Clara, Monteleone, Francesca, Zambrano, Nicola, Fontanini, Gabriella, Servadio, Adele, Pignataro, Giuseppe, Grumetto, Lucia, Lavecchia, Antonio, Bruzzese, Dario, Iaccarino, Antonino, Troncone, Giancarlo, Veneziani, Bianca Maria, Montuori, Nunzia, Placido, Sabino De, Bianco, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571185/ https://www.ncbi.nlm.nih.gov/pubmed/28839232 http://dx.doi.org/10.1038/s41598-017-10062-1 |
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