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Hypoxia-inducible ERO1α promotes cancer progression through modulation of integrin-β1 modification and signalling in HCT116 colorectal cancer cells

Endoplasmic reticulum disulphide oxidase 1α (ERO1α) is an oxidase localized in the endoplasmic reticulum that plays a role in the formation of disulphide bonds of secreted and cell-surface proteins. We previously showed that ERO1α is overexpressed in various types of cancer and we further identified...

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Detalles Bibliográficos
Autores principales: Takei, Norio, Yoneda, Akihiro, Sakai-Sawada, Kaori, Kosaka, Marina, Minomi, Kenjiro, Tamura, Yasuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571208/
https://www.ncbi.nlm.nih.gov/pubmed/28839225
http://dx.doi.org/10.1038/s41598-017-09976-7