In Vivo Biomarker Analysis of the Effects of Intranasally Dosed PC945, a Novel Antifungal Triazole, on Aspergillus fumigatus Infection in Immunocompromised Mice

PC945 is a novel triazole optimized for lung delivery, and the objective of this study is to determine the effects of intranasally dosed PC945 on Aspergillus fumigatus infection and associated biomarkers in immunocompromised mice. PC945, posaconazole, or voriconazole was administered intranasally on...

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Detalles Bibliográficos
Autores principales: Kimura, Genki, Nakaoki, Takahiro, Colley, Thomas, Rapeport, Garth, Strong, Pete, Ito, Kazuhiro, Kizawa, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571324/
https://www.ncbi.nlm.nih.gov/pubmed/28630185
http://dx.doi.org/10.1128/AAC.00124-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571324/
https://www.ncbi.nlm.nih.gov/pubmed/28630185
http://dx.doi.org/10.1128/AAC.00124-17

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