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Development, functional characterization and validation of methodology for GMP-compliant manufacture of phagocytic macrophages: A novel cellular therapeutic for liver cirrhosis

BACKGROUND AIMS: Autologous macrophage therapy represents a potentially significant therapeutic advance for the treatment of severe progressive liver cirrhosis. Administration of macrophages has been shown to reduce inflammation and drive fibrotic scar breakdown and tissue repair in relevant models....

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Detalles Bibliográficos
Autores principales: Fraser, Alasdair R., Pass, Chloe, Burgoyne, Paul, Atkinson, Anne, Bailey, Laura, Laurie, Audrey, W.A. McGowan, Neil, Hamid, Akib, Moore, Joanna K., Dwyer, Benjamin J., Turner, Marc L., Forbes, Stuart J., Campbell, John D.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571439/
https://www.ncbi.nlm.nih.gov/pubmed/28673774
http://dx.doi.org/10.1016/j.jcyt.2017.05.009