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The Proteasome in Modern Drug Discovery: Second Life of a Highly Valuable Drug Target
[Image: see text] As the central figure of the cellular protein degradation machinery, the proteasome is critical for cell survival. Having been extensively targeted for inhibition, the constitutive proteasome has proven its role as a highly valuable drug target. However, recent advances in the prot...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571462/ https://www.ncbi.nlm.nih.gov/pubmed/28852696 http://dx.doi.org/10.1021/acscentsci.7b00252 |