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Cryptotanshinone inhibition of mammalian target of rapamycin pathway is dependent on oestrogen receptor alpha in breast cancer

Cryptotanshinone (CPT) has been demonstrated to inhibit proliferation and mammalian target of rapamycin (mTOR) pathway in MCF‐7 breast cancer cells. However, the same results are unable to be repeated in MDA‐MB‐231 cells. Given the main difference of oestrogen receptor α (ERα) between two types of b...

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Detalles Bibliográficos
Autores principales: Pan, Yanhong, Shi, Junfeng, Ni, Wenting, Liu, Yuping, Wang, Siliang, Wang, Xu, Wei, Zhonghong, Wang, Aiyun, Chen, Wenxing, Lu, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571522/
https://www.ncbi.nlm.nih.gov/pubmed/28272775
http://dx.doi.org/10.1111/jcmm.13135