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Histone deacetylase inhibitors promote eNOS expression in vascular smooth muscle cells and suppress hypoxia‐induced cell growth

Hypoxia stimulates excessive growth of vascular smooth muscle cells (VSMCs) contributing to vascular remodelling. Recent studies have shown that histone deacetylase inhibitors (HDIs) suppress VSMC proliferation and activate eNOS expression. However, the effects of HDI on hypoxia‐induced VSMC growth...

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Detalles Bibliográficos
Autores principales: Tan, Xiaoling, Feng, Lan, Huang, Xiaoyong, Yang, Yidong, Yang, Chengzhong, Gao, Yuqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571528/
https://www.ncbi.nlm.nih.gov/pubmed/28266122
http://dx.doi.org/10.1111/jcmm.13122