Cargando…

TNF‐α promotes survival and migration of MSCs under oxidative stress via NF‐κB pathway to attenuate intimal hyperplasia in vein grafts

The oxidative stress caused by endothelial injury is involved in intimal hyperplasia (IH) in vein grafts. Mesenchymal stem cells (MSCs) can home to injured intima and promote endothelial repair. However, MSC apoptosis is increased accompanied by decreased functional activity under oxidative stress....

Descripción completa

Detalles Bibliográficos
Autores principales: Bai, Xiao, Xi, Jie, Bi, Yanwen, Zhao, Xin, Bing, Weidong, Meng, Xiangbin, Liu, Yimin, Zhu, Zhonglai, Song, Guangmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571532/
https://www.ncbi.nlm.nih.gov/pubmed/28266177
http://dx.doi.org/10.1111/jcmm.13131