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The activity of the carbamoyl phosphate synthase 1 promoter in human liver‐derived cells is dependent on hepatocyte nuclear factor 3‐beta

Carbamoyl phosphate synthase 1 (CPS1) is the rate‐limiting enzyme in the first step of the urea cycle and an indispensable enzyme in the metabolism of human liver. However, CPS1 epigenetic regulation involves promoter analysis and the role of liver‐enriched transcription factors (LETFs), which is no...

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Detalles Bibliográficos
Autores principales: Chen, Zhanfei, Tang, Nanhong, Wang, Xiaoqian, Chen, Yanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571533/
https://www.ncbi.nlm.nih.gov/pubmed/28272778
http://dx.doi.org/10.1111/jcmm.13123