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Comparative RNA‐Seq transcriptome analyses reveal distinct metabolic pathways in diabetic nerve and kidney disease

Treating insulin resistance with pioglitazone normalizes renal function and improves small nerve fibre function and architecture; however, it does not affect large myelinated nerve fibre function in mouse models of type 2 diabetes (T2DM), indicating that pioglitazone affects the body in a tissue‐spe...

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Detalles Bibliográficos
Autores principales: Hinder, Lucy M., Park, Meeyoung, Rumora, Amy E., Hur, Junguk, Eichinger, Felix, Pennathur, Subramaniam, Kretzler, Matthias, Brosius, Frank C., Feldman, Eva L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571536/
https://www.ncbi.nlm.nih.gov/pubmed/28272773
http://dx.doi.org/10.1111/jcmm.13136