Cargando…

Comparative RNA‐Seq transcriptome analyses reveal distinct metabolic pathways in diabetic nerve and kidney disease

Treating insulin resistance with pioglitazone normalizes renal function and improves small nerve fibre function and architecture; however, it does not affect large myelinated nerve fibre function in mouse models of type 2 diabetes (T2DM), indicating that pioglitazone affects the body in a tissue‐spe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hinder, Lucy M., Park, Meeyoung, Rumora, Amy E., Hur, Junguk, Eichinger, Felix, Pennathur, Subramaniam, Kretzler, Matthias, Brosius, Frank C., Feldman, Eva L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571536/ https://www.ncbi.nlm.nih.gov/pubmed/28272773 http://dx.doi.org/10.1111/jcmm.13136

Ejemplares similares

The Metabolic Syndrome and Microvascular Complications in a Murine Model of Type 2 Diabetes
por: Hur, Junguk, et al.
Publicado: (2015)

Integrated lipidomic and transcriptomic analyses identify altered nerve triglycerides in mouse models of prediabetes and type 2 diabetes
por: O'Brien, Phillipe D., et al.
Publicado: (2020)

Gut microbiota in a mouse model of obesity and peripheral neuropathy associated with plasma and nerve lipidomics and nerve transcriptomics
por: Guo, Kai, et al.
Publicado: (2023)

A High-Fat Diet Disrupts Nerve Lipids and Mitochondrial Function in Murine Models of Neuropathy
por: Rumora, Amy E., et al.
Publicado: (2022)

Transcriptomic analysis of diabetic kidney disease and neuropathy in mouse models of type 1 and type 2 diabetes
por: Elzinga, Sarah E., et al.
Publicado: (2023)

Targeted Lipidomic and Transcriptomic Analysis Identifies Dysregulated Renal Ceramide Metabolism in a Mouse Model of Diabetic Kidney Disease
por: Sas, Kelli M, et al.
Publicado: (2015)

Mitochondrial uncoupling has no effect on microvascular complications in type 2 diabetes
por: Hinder, Lucy M., et al.
Publicado: (2019)

Differential Effects of Empagliflozin on Microvascular Complications in Murine Models of Type 1 and Type 2 Diabetes
por: Eid, Stephanie A., et al.
Publicado: (2020)

COVID-19 and Diabetes: A Collision and Collusion of Two Diseases
por: Feldman, Eva L., et al.
Publicado: (2020)

Genome-wide DNA methylation profiling of human diabetic peripheral neuropathy in subjects with type 2 diabetes mellitus
por: Guo, Kai, et al.
Publicado: (2019)

Transcriptional Profiling of Diabetic Neuropathy in the BKS db/db Mouse: A Model of Type 2 Diabetes
por: Pande, Manjusha, et al.
Publicado: (2011)

Differential effects of minocycline on microvascular complications in murine models of type 1 and type 2 diabetes
por: Eid, Stephanie A., et al.
Publicado: (2020)

Conserved Transcriptional Signatures in Human and Murine Diabetic Peripheral Neuropathy
por: McGregor, Brett A., et al.
Publicado: (2018)

Formal Concept Analysis of Disease Similarity
por: Keller, Benjamin J., et al.
Publicado: (2012)

Identification of Factors Associated With Sural Nerve Regeneration and Degeneration in Diabetic Neuropathy
por: Hur, Junguk, et al.
Publicado: (2013)

Patch-to-Seq and Transcriptomic Analyses Yield Molecular Markers of Functionally Distinct Brainstem Serotonin Neurons
por: Mouradian, Gary C., et al.
Publicado: (2022)

Integrating Automated Workflows, Human Intelligence and Collaboration
por: Mirel, Barbara, et al.
Publicado: (2009)

Juvenile murine models of prediabetes and type 2 diabetes develop neuropathy
por: O'Brien, Phillipe D., et al.
Publicado: (2018)

A cognitive task analysis of a visual analytic workflow: Exploring molecular interaction networks in systems biology
por: Mirel, Barbara, et al.
Publicado: (2011)

Transcriptome-based network analysis reveals renal cell type-specific dysregulation of hypoxia-associated transcripts
por: Shved, Natallia, et al.
Publicado: (2017)

Consent for Genetic Biobanking in a Diverse Multisite CKD Cohort
por: Troost, Jonathan P., et al.
Publicado: (2018)

The deacylase sirtuin 5 reduces malonylation in nonmitochondrial metabolic pathways in diabetic kidney disease
por: Baek, Judy, et al.
Publicado: (2023)

Ontology-based Brucella vaccine literature indexing and systematic analysis of gene-vaccine association network
por: Hur, Junguk, et al.
Publicado: (2011)

Network analysis of genes regulated in renal diseases: implications for a molecular-based classification
por: Bhavnani, Suresh K, et al.
Publicado: (2009)

Repurposable drugs for SARS-CoV-2 and influenza sepsis with scRNA-seq data targeting post-transcription modifications
por: Wang, Zhihan, et al.
Publicado: (2021)

Cytoplasmic TDP43 Binds microRNAs: New Disease Targets in Amyotrophic Lateral Sclerosis
por: Paez-Colasante, Ximena, et al.
Publicado: (2020)

SciMiner: web-based literature mining tool for target identification and functional enrichment analysis
por: Hur, Junguk, et al.
Publicado: (2009)

Urine Glycoprotein Profile Reveals Novel Markers for Chronic Kidney Disease
por: Vivekanandan-Giri, Anuradha, et al.
Publicado: (2011)

Multi-Scalar Data Integration Links Glomerular Angiopoietin-Tie Signaling Pathway Activation With Progression of Diabetic Kidney Disease
por: Liu, Jiahao, et al.
Publicado: (2022)

An RNA-sequencing transcriptome of the rodent Schwann cell response to peripheral nerve injury
por: Brosius Lutz, Amanda, et al.
Publicado: (2022)

Systematically Differentiating Functions for Alternatively Spliced Isoforms through Integrating RNA-seq Data
por: Eksi, Ridvan, et al.
Publicado: (2013)

Shiny-Seq: advanced guided transcriptome analysis
por: Sundararajan, Zenitha, et al.
Publicado: (2019)

Urinary 2-Hydroxyglutarate Enantiomers Are Markedly Elevated in a Murine Model of Type 2 Diabetic Kidney Disease
por: Baek, Judy, et al.
Publicado: (2021)

Whole transcriptome analyses of six thoroughbred horses before and after exercise using RNA-Seq
por: Park, Kyung-Do, et al.
Publicado: (2012)

PubChemSR: A search and retrieval tool for PubChem
por: Hur, Junguk, et al.
Publicado: (2008)

Discovering hidden relationships between renal diseases and regulated genes through 3D network visualizations
por: Bhavnani, Suresh K, et al.
Publicado: (2010)

Correction to: Pathway crosstalk perturbation network modeling for identification of connectivity changes induced by diabetic neuropathy and pioglitazone
por: de Anda-Jáuregui, Guillermo, et al.
Publicado: (2019)

Pathway crosstalk perturbation network modeling for identification of connectivity changes induced by diabetic neuropathy and pioglitazone
por: de Anda-Jáuregui, Guillermo, et al.
Publicado: (2019)

Genome-wide profiling of DNA methylation and gene expression identifies candidate genes for human diabetic neuropathy
por: Guo, Kai, et al.
Publicado: (2020)

Correction to: Genome-wide profiling of DNA methylation and gene expression identifies candidate genes for human diabetic neuropathy
por: Guo, Kai, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_cakmm2okq039coh9d2ksr1gj1e