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The pathogenicity of T cell epitopes on human Goodpasture antigen and its critical amino acid motif

Goodpasture antigen, the non‐collagenous domain of α3 chain of type IV collagen [α3(IV)NC1], is the target antigen of anti‐glomerular basement membrane (GBM) antibodies. The pathogenicity of T cell epitopes is not elucidated clearly. In this study, we aim to define the nephritogenic T cell epitopes...

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Detalles Bibliográficos
Autores principales: Hu, Shui‐yi, Gu, Qiu‐hua, Wang, Jia, Wang, Miao, Jia, Xiao‐yu, Cui, Zhao, Zhao, Ming‐hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571546/
https://www.ncbi.nlm.nih.gov/pubmed/28296059
http://dx.doi.org/10.1111/jcmm.13134