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NKG2D ligand RAE1ε induces generation and enhances the inhibitor function of myeloid‐derived suppressor cells in mice

Expression of surface NKG2D ligands on tumour cells, which activates nature killer (NK) cells and CD8(+) T cells, is crucial in antitumour immunity. Some types of tumours have evolved mechanisms to suppress NKG2D‐mediated immune cell activation, such as tumour‐derived soluble NKG2D ligands or sustai...

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Detalles Bibliográficos
Autores principales: Qian, Li, Liu, Yang, Wang, Shaoqing, Gong, Weijuan, Jia, Xiaoqin, Liu, Lu, Ye, Feng, Ding, Jingjuan, Xu, Yuwei, Fu, Yi, Tian, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571551/
https://www.ncbi.nlm.nih.gov/pubmed/28276625
http://dx.doi.org/10.1111/jcmm.13124