Cargando…

Tetrandrine, an agonist of aryl hydrocarbon receptor, reciprocally modulates the activities of STAT3 and STAT5 to suppress Th17 cell differentiation

Tetrandrine, a bisbenzylisoquinoline alkaloid constituent of the root of Stephania tetrandra S. Moore, was previously shown to suppress the differentiation of T helper 17 (Th17) cells and consequently ameliorate the collagen‐induced arthritis (CIA) in mice by activating the aryl hydrocarbon receptor...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Xusheng, Dou, Yannong, Wu, Xin, Wei, Zhifeng, Dai, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571555/
https://www.ncbi.nlm.nih.gov/pubmed/28332288
http://dx.doi.org/10.1111/jcmm.13141